Ethyl 1-benzyl-3-(chloromethyl)azetidine-3-carboxylate CAS 137266-85-4
| CAS No. | 137266-85-4 |
| Molecular Formula | C14H18ClNO2 |
| Molecular Weight | 267.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 1-benzyl-3-(chloromethyl)azetidine-3-carboxylate.
CATO supplies Ethyl 1-benzyl-3-(chloromethyl)azetidine-3-carboxylate (CAS 137266-85-4), a certified reference material (molecular formula C14H18ClNO2, MW 267.75 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 1-benzyl-3-(chloromethyl)azetidine-3-carboxylate (C14H18ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ethyl 1-benzyl-3-(chloromethyl)azetidine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18ClNO2 |
| Molecular Weight | 267.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Benzyl 4-(chloromethyl)piperidine-1-carboxylate (CAS 1353968-97-4)
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- Benzyl (4-chlorocyclohexyl)carbamate (CAS 1353952-79-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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