5-(2-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid CAS 1373223-67-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1373223-67-6
Molecular FormulaC10H8BrN3O2
Molecular Weight282.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(2-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid CAS 1373223-67-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 282.09 g/mol gives 5-(2-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-(2-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid (CAS 1373223-67-6), molecular formula C10H8BrN3O2 and molecular weight 282.09 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(2-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid (C10H8BrN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(2-Bromophenyl)-1-methyl-1H-1,2,4-triazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8BrN3O2
Molecular Weight282.09 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentBr-containing
Nitrogen Atoms3

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