6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride CAS 1373223-69-8
| CAS No. | 1373223-69-8 |
| Molecular Formula | C10H12FN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 201.67 g/mol gives 6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride (CAS 1373223-69-8) is a high-purity analytical reference standard with the molecular formula C10H12FNHCl and a molecular weight of 201.67 g/mol.
6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride (C10H12FNHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12FN HCl |
| Molecular Weight | 201.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
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- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- 1-Amino-2-methylnaphthalene Hydrochloride (CAS 111180-78-0)
- 5-Amino-3-(3,5-dichlorophenyl)isoxazole (CAS 1020997-14-1)
- 2-Amino-1-naphthalenesulfonic Acid (CAS 81-16-3)
- 4,6-Dichloro-3-isopropyl-2-methylquinoline (CAS 1339375-48-2)
- tert-Butyl ((1S,3R)-3-(aminomethyl)cyclopentyl)carbamate (CAS 774213-03-5)
- 3-Tert-butyl-4-methyl-1-phenyl-1h-pyrazol-5-amine hydrochloride (CAS 1303889-63-5)
- tert-Butyl 4-(2-methoxyethyl)piperidine-1-carboxylate (CAS 509147-79-9)
- 4-Oxo-8-(1H-pyrrol-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 89353-47-9)
- Boc-Ala-Pro-Nva-4-chloro-SBzl (CAS 90171-50-9)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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