(1R)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride CAS 1373232-18-8
| CAS No. | 1373232-18-8 |
| Molecular Formula | C10H12FN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (1R)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride (CAS 1373232-18-8), a certified reference material (molecular formula C10H12FNHCl, MW 201.67 g/mol) for analytical method development and quality control.
Structurally, (1R)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine hydrochloride (C10H12FNHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 201.67 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12FN HCl |
| Molecular Weight | 201.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
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- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
- Ethyl 4-fluoro-3-ethoxybenzoate (CAS 1000207-63-5)
- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 1-(5-Fluoro-2-methylphenyl)pyrrolidine (CAS 1000339-32-1)
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- 2-Chloro-7-iodo-5-(triisopropylsilyl)-5H-pyrrolo[2,3-b]pyrazine (CAS 1184852-48-9)
- tert-butyl N-{[(2S,5R)-5-aminooxan-2-yl]methyl}carbamate (CAS 1638744-98-5)
- Rivastigmine-d3 (CAS 1133229-21-6)
- N-Carbamimidoylmorpholine-4-carboximidamide (CAS 3731-59-7)
- 5-(2-Chloroethyl)tetrazole (CAS 18755-46-9)
- 3-epi-Ursolic Acid (CAS 989-30-0)
- Camphor Impurity 9 (CAS CATO-C4X-21149)
- potassium 5-cyclopropyl-1,3,4-oxadiazole-2-carboxylate (CAS 1989671-27-3)
- 1H,2H-pyrrolo[1,2-a]pyrazin-1-one (CAS 136927-63-4)
- Tirzepatide Impurity 52 (CAS CATO-C4X-324052)
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