Ethyl 6-cyano-2-methylnicotinate CAS 137347-35-4
| CAS No. | 137347-35-4 |
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ethyl 6-cyano-2-methylnicotinate (CAS 137347-35-4), a certified reference material (molecular formula C10H10N2O2, MW 190.20 g/mol) for analytical method development and quality control.
Ethyl 6-cyano-2-methylnicotinate (C10H10N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 6-cyano-2-methylnicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
Related Ethyl Standards
- Ethyl 5-cyano-2-methylnicotinate (CAS 103038-00-2)
- ethyl 5-cyano-6-methylpyridine-3-carboxylate (CAS 106944-54-1)
- 4-Cyano-N-methoxy-N-methylbenzamide (CAS 116332-64-0)
- 3-Cyano-4-hydroxy-N,N-dimethylbenzamide (CAS 1243279-44-8)
- 2-Cyano-3-hydroxy-N,N-dimethylbenzamide (CAS 1243279-47-1)
- 2-Cyano-4-hydroxy-N,N-dimethylbenzamide (CAS 1243371-57-4)
- 5-Cyano-2-hydroxy-N,N-dimethylbenzamide (CAS 1243388-08-0)
- Cyano-N'-(2-hydroxyethyl)nicotinimidamide (CAS 138772-58-4)
Recommended Standards
- Methyl 5-methyl-1h-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 1373228-85-3)
- tert-butyl N-(2-nitroethyl)carbamate (CAS 1374160-25-4)
- 2-Ethyl-7-hydroxy-4H-chromen-4-one (CAS 137215-31-7)
- 5-(2-(Furan-2-yl)vinyl)-3-methylisoxazol-4-amine (CAS 1374409-02-5)
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- (Z)-N-benzyl-2-cyano-3-(2-fluorophenyl)-2-propenamide (CAS 358314-77-9)
- 6-Fluoro-4,8-dimethylquinoline (CAS 1420791-11-2)
- 6-(Azepan-1-yl)-4-methylnicotinonitrile (CAS 1355195-62-8)
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