3,3-Difluoro-4-methoxypiperidine CAS 1373609-11-0
| CAS No. | 1373609-11-0 |
| Molecular Formula | C6H11F2NO |
| Molecular Weight | 151.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3,3-Difluoro-4-methoxypiperidine is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3,3-Difluoro-4-methoxypiperidine (CAS 1373609-11-0), molecular formula C6H11F2NO and molecular weight 151.15 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H11F2NO, 3,3-Difluoro-4-methoxypiperidine contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 151.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3-Difluoro-4-methoxypiperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H11F2NO |
| Molecular Weight | 151.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,3-difluoro-4-methoxy-pyridine (CAS 1227578-88-2)
- [(2R)-4,4-difluoro-1-methylpyrrolidin-2-yl]methanol (CAS 1408002-86-7)
- (S)-4,4-Difluoro-1-methylpyrrolidine-2-methanol (CAS 1408057-44-2)
- 3,3-Difluoro-1-methylpiperidin-4-ol (CAS 1504212-61-6)
- (4,4-Difluoro-1-methylpyrrolidin-3-yl)methanol (CAS 1784503-73-6)
- 4,4-difluoro-1-methylpiperidin-3-ol (CAS 1785484-23-2)
- 5,5-Difluoro-1-methylpiperidin-3-ol (CAS 1866148-86-8)
- (R)-3,3-Difluoro-1-methylpiperidin-4-ol (CAS 2306252-98-0)
Recommended Standards
- (1-(Aminomethyl)-3,3-difluorocyclobutyl)methanol (CAS 1363383-40-7)
- (1R,6S)-6-amino-2,2-difluorocyclohexan-1-ol (CAS 1374973-14-4)
- (5,5-Difluoropiperidin-3-yl)methanol (CAS 1356338-40-3)
- 2-amino-1-(3,3-difluorocyclobutyl)ethan-1-ol (CAS 1375710-53-4)
- DDe-l-alaninol (CAS 1272755-17-5)
- 3'-Fluoro-6-methyl-[1,1'-biphenyl]-3-carboxylic acid (CAS 1214331-53-9)
- 3-(1H-Benzo[d]imidazol-2-yl)propanenitrile (CAS 51100-82-4)
- 1-Amino-2-methyl-4-(p-tolylamino)anthracene-9,10-dione (CAS 116-77-8)
- 6-Amino-2-(cyclohexylamino)pyrimidin-4(3H)-one (CAS 1256628-12-2)
- Ethyl 4,5-dibromothiophene-2-carboxylate (CAS 62224-25-3)
- 2-Carboethoxy-3-(3,4,5-trifluorophenyl)-propiophenone (CAS 898777-76-9)
- N-(2-Aminophenyl)-4-((7-fluoro-1H-indazol-1-yl)methyl)benzamide (CAS 920315-05-5)
- 2,4-Difluorophenyl ethyl carbonate (CAS 152169-43-2)
- Mitogenic Pentapeptide (CAS 87173-03-3)
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