5-(3,4-Dichlorophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid CAS 1373754-96-1
| CAS No. | 1373754-96-1 |
| Molecular Formula | C14H8Cl2F3NO3 |
| Molecular Weight | 366.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H8Cl2F3NO3, 5-(3,4-Dichlorophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 366.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-(3,4-Dichlorophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid (CAS 1373754-96-1) is a high-purity analytical reference standard with the molecular formula C14H8Cl2F3NO3 and a molecular weight of 366.12 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(3,4-Dichlorophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2F3NO3 |
| Molecular Weight | 366.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-(Carboxymethoxy)-3-ethoxy-5-iodobenzoic acid (CAS 713104-49-5)
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- Win 18446 (CAS 1477-57-2)
- 2-(2,5-Dimethyl-1H-pyrrol-1-yl)-5-iodo-4-(trifluoromethyl)pyridine (CAS 2209066-05-5)
- 2-Chloro-N-(2-ethylphenyl)benzamide (CAS 196804-11-2)
- (E)-4-Amino-6-((4-(benzyloxy)-3-chlorophenyl)amino)pyrimidine-5-carbaldehyde O-(2-morpholinoethyl) oxime (CAS 944341-54-2)
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(3,5-dimethylphenoxy)pyrrolidine-2-carboxylic acid (CAS 869682-05-3)
- N-nitroso Peramivir Impurity 99 (CAS CATO-C4X-183399)
- tert-Butyl 2-(2-aminopyridin-3-yl)piperidine-1-carboxylate (CAS 1352526-05-6)
- Tert-butyl 4-(3-bromo-5-(methoxycarbonyl)pyridin-2-yl)piperazine-1-carboxylate (CAS 906559-32-8)
- N-Nitroso Etilefrine EP Impurity F (CAS 20689-96-7)
- 2-(Ethylamino)-6-fluorobenzonitrile (CAS 119584-72-4)
- 3-Fluorocyclobutan-1-amine (CAS 1234616-60-4)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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