2-chloro-6-(1-ethoxyethoxy)quinoline CAS 1374109-24-6

Description

The occurrence of 2-chloro-6-(1-ethoxyethoxy)quinoline is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-chloro-6-(1-ethoxyethoxy)quinoline (CAS 1374109-24-6), molecular formula C13H24ClNO2 and molecular weight 261.79 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-chloro-6-(1-ethoxyethoxy)quinoline (C13H24ClNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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