(2S,4R)-1-(tert-butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)-2-methylpyrrolidine-2-carboxylic acid CAS 1374161-77-9
| CAS No. | 1374161-77-9 |
| Molecular Formula | C17H33NO5Si |
| Molecular Weight | 359.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2S,4R)-1-(tert-butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)-2-methylpyrrolidine-2-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2S,4R)-1-(tert-butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)-2-methylpyrrolidine-2-carboxylic acid (CAS 1374161-77-9) is a high-purity analytical reference standard with the molecular formula C17H33NO5Si and a molecular weight of 359.53 g/mol.
The molecular framework of (2S,4R)-1-(tert-butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)-2-methylpyrrolidine-2-carboxylic acid (C17H33NO5Si) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2S,4R)-1-(tert-butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)-2-methylpyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H33NO5Si |
| Molecular Weight | 359.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,3S)-1-(tert-butoxycarbonyl)-3-((tert-butyldimethylsilyl)oxy)piperidine-2-carboxylic acid (CAS 1262985-28-3)
- tert-Butyl 3-((tert-butyldimethylsilyl)oxy)-6-hydroxyhexahydro-4H-furo[3,2-b]pyrrole-4-carboxylate (CAS 1544206-88-3)
- 1-(Tert-butyl) 2-methyl (2R,4R)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1,2-dicarboxylate (CAS 114760-51-9)
- 2-(Benzylthio)-N-((2-methoxyadamantan-2-yl)methyl)acetamide (CAS 1797560-88-3)
- 2-Ethynyl-1,3-difluorobenzene (CAS 381723-16-6)
- Boc-β-HoArg(Pbf)-OH (CAS 1998216-44-6)
- 1-Methyl-1H-furo[3,4-b]pyrrole-4,6-dione (CAS 168543-12-2)
- 1-Chloro-7-iodoheptane (CAS 99669-96-2)
- 4-Chloro-3-methoxyisothiazole (CAS 78383-41-2)
- 4-(Methylamino)cyclohexanol (CAS 2987-05-5)
- Tert-butyl 4-(3,5-dimethoxyphenyl)piperazine-1-carboxylate (CAS 1121596-71-1)
- 1-[3-(aminomethyl)pyrrolidin-1-yl]-2,2-dimethylpropan-1-one (CAS 1339164-60-1)
- 2-((4-Amino-5-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-phenoxyphenyl)acetamide (CAS 573695-15-5)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
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