1-(2-Amino-3-chloro-5-fluorophenyl)ethanone CAS 1374194-27-0
| CAS No. | 1374194-27-0 |
| Molecular Formula | C8H7ClFNO |
| Molecular Weight | 187.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-(2-Amino-3-chloro-5-fluorophenyl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1-(2-Amino-3-chloro-5-fluorophenyl)ethanone (CAS 1374194-27-0) is a high-purity analytical reference standard with the molecular formula C8H7ClFNO and a molecular weight of 187.60 g/mol.
Based on its molecular formula C8H7ClFNO, 1-(2-Amino-3-chloro-5-fluorophenyl)ethanone contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 187.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7ClFNO |
| Molecular Weight | 187.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- 1-(5-Amino-2-chloro-4-fluorophenyl)ethan-1-one (CAS 101949-89-7)
- 1-(4-Amino-2-chloro-5-fluorophenyl)ethanone (CAS 1260657-47-3)
- 2-Amino-1-(2-chloro-4-fluorophenyl)ethan-1-one (CAS 1343003-67-7)
- 2-Amino-1-(5-chloro-2-fluorophenyl)ethan-1-one (CAS 1368558-34-2)
- 2-Amino-5-chloro-4-fluoro-3-methylbenzaldehyde (CAS 1415597-14-6)
- 1-(2-Amino-4-chloro-5-fluorophenyl)ethan-1-one (CAS 937816-87-0)
- 1-(2-amino-4-fluorophenyl)-2-chloroethan-1-one (CAS 68438-32-4)
- 1-(2-amino-6-fluorophenyl)-2-chloroethan-1-one (CAS 68438-31-3)
Recommended Standards
- 1-(4-(Chloromethyl)-6-fluoropyridin-2-yl)ethan-1-one (CAS 1393548-16-7)
- 4-Chloro-2-fluoro-N-methylbenzamide (CAS 1343038-33-4)
- 1-(2-(Chloromethyl)-6-fluoropyridin-4-yl)ethan-1-one (CAS 1393568-36-9)
- 2-chloro-2-(4-fluorophenyl)acetamide (CAS 1396988-05-8)
- N-(2,5-difluorophenyl)-2,6-difluoro-3-nitrobenzamide (CAS 260553-00-2)
- Butylmalonic Acid (CAS 534-59-8)
- 2-Amino-N-(4-(trifluoromethoxy)phenyl)benzamide (CAS 263559-01-9)
- 2,1,3-Benzothiadiazole-4-carbonyl chloride (CAS 148563-33-1)
- 5-Chloro-n-(3-ethynylphenyl)thiophene-2-sulfonamide (CAS 1061371-88-7)
- (S)-3-((tert-butoxycarbonyl)amino)-2-(3-fluorobenzyl)propanoic acid (CAS 1260607-53-1)
- 4-(2-Methylphenyl)-1,2,5-oxadiazol-3-amine (CAS 22899-59-8)
- 2-Amino-N-(1-isobutyl-1H-pyrazol-4-yl)acetamide (CAS 1707364-72-4)
- 4-Chloro-6-[3,4-dihydro-2(1H)-isoquinolinyl]-1,3,5-triazin-2-amine (CAS 1219971-91-1)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com