3-(trifluoromethyl)-1H-indazole-5-carboxylic acid CAS 1374258-59-9
| CAS No. | 1374258-59-9 |
| Molecular Formula | C9H13F3N2O2 |
| Molecular Weight | 238.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(trifluoromethyl)-1H-indazole-5-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(trifluoromethyl)-1H-indazole-5-carboxylic acid (CAS 1374258-59-9), molecular formula C9H13F3N2O2 and molecular weight 238.21 g/mol, is a CATO reference standard with documented purity and traceability.
3-(trifluoromethyl)-1H-indazole-5-carboxylic acid (C9H13F3N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(trifluoromethyl)-1H-indazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13F3N2O2 |
| Molecular Weight | 238.21 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
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Recommended Standards
- 4-[4-(trifluoromethyl)phenyl]pyridin-3-amine (CAS 1354962-52-9)
- 4-(3-(Trifluoromethyl)phenyl)pyridin-3-amine (CAS 1374664-88-6)
- 2,2,2-Trifluoro-1-(2-methylnaphthalen-1-yl)ethanone (CAS 131831-98-6)
- 2-Benzyl-4-(trifluoromethyl)pyrimidine (CAS 1411762-99-6)
- Diethyl 2-((2-ethoxy-2-oxoethyl)thio)succinate (CAS 909772-87-8)
- 1,4-Dichloro-2-difluoromethoxy-6-fluorobenzene (CAS 1803832-21-4)
- 3-(5-((2-Ethyl-1H-imidazol-1-yl)methyl)-1,2,4-oxadiazol-3-yl)benzaldehyde (CAS 1258652-75-3)
- 3-(2,4-Dimethylphenyl)-1,2,4-oxadiazole-5-carbaldehyde (CAS 1774899-90-9)
- 2-Aminopent-4-enamide (CAS 144073-06-3)
- 1,2-Dimethyl-5-phenyl-1h-pyrrole-3-carboxylic acid (CAS 65473-92-9)
- 2-(3-Cyano-5-fluorophenyl)butanoic acid (CAS 1515749-88-8)
- N-(2-Fluorobenzyl)-3-propoxyaniline (CAS 1040684-14-7)
- 3-Fluoro-5-(pentafluoro-lambda6-sulfanyl)benzaldehyde (CAS 1240257-92-4)
- [α-Glu](Sidechain trans-position)-Liraglutide (CAS CATO-C4X-199240)
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