ethyl 2-chloroquinoline-7-carboxylate CAS 1374258-79-3
| CAS No. | 1374258-79-3 |
| Molecular Formula | C12H20ClNO2 |
| Molecular Weight | 245.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
ethyl 2-chloroquinoline-7-carboxylate (CAS 1374258-79-3) is a high-purity analytical reference standard with the molecular formula C12H20ClNO2 and a molecular weight of 245.75 g/mol.
ethyl 2-chloroquinoline-7-carboxylate (C12H20ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H20ClNO2 |
| Molecular Weight | 245.75 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related ethyl Standards
- 8-Chloroquinoline-5-sulfonic acid (CAS 129305-09-5)
- 4-Chloroquinoline-3-sulfonic acid (CAS 205985-49-5)
- 4-Chloroquinoline-8-sulfonic acid (CAS 71331-01-6)
- 5-Chloroquinoline-8-sulfonic acid (CAS 90225-09-5)
- 8-Chloroquinoline-5-sulfonamide (CAS 1099660-83-9)
- 2-Chloroquinoline-6-sulfonamide (CAS 1156387-51-7)
- 6-chloroquinoline-3-sulfonamide (CAS 1798707-42-2)
- 5-Chloroquinoline-8-sulfonamide (CAS 299439-20-6)
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- 1,3-Dimethyl-1-{3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl}urea (CAS 1000929-95-2)
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