N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine CAS 1374507-24-0
| CAS No. | 1374507-24-0 |
| Molecular Formula | C11H8ClF3N4 |
| Molecular Weight | 288.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine.
N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine (CAS 1374507-24-0) is a high-purity analytical reference standard with the molecular formula C11H8ClF3N4 and a molecular weight of 288.66 g/mol.
The molecular framework of N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine (C11H8ClF3N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClF3N4 |
| Molecular Weight | 288.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 6-chloro-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)purine (CAS 150863-84-6)
- N2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)pyridine-2,6-diamine (CAS 477864-63-4)
- (S)-6-chloro-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide (CAS 1247939-81-6)
- N-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)-N-methylmethanesulfonamide (CAS 1311280-32-6)
- 1-Acetyl-4-chloro-3-phenyl-5-(trifluoromethyl)-1H-pyrazole (CAS 1017793-56-4)
- 3-Chloro-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 1099669-15-4)
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Recommended Standards
- (2R,3R,4S,5R)-5-(6-Chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 135473-21-1)
- 6-(chloromethyl)-2-[4-(trifluoromethyl)phenyl]pyrimidin-4-ol (CAS 261959-08-4)
- 3-(4-nitrophenyl)-1,2-oxazole-5-sulfonyl chloride (CAS 1909337-76-3)
- 5-Chloro-3-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbaldehyde (CAS 376359-52-3)
- furo[2,3-b]pyridine-4-carboxylic acid (CAS 1500260-63-8)
- 4-(4-Bromophenoxy)-2-(hydroxymethyl)butyl 4-methylbenzenesulfonate (CAS 1467061-84-2)
- Methyl n-Octanoate (CAS 111-11-5)
- cis-1,4-Dichlorobutane-2,3-diol (CAS 40227-39-2)
- 1H-Benzo[de]thiazolo[5,4-g]isoquinoline (CAS 169147-51-7)
- (2E)-3-(5-methanesulfonylfuran-2-yl)prop-2-enoic acid (CAS 111252-34-7)
- 3-(3-Bromophenyl)oxazolidin-2-one (CAS 1086221-37-5)
- 3-(2,6-Dimethylphenoxy)azetidine hydrochloride (CAS 143482-46-6)
- 1-Isoxazol-4-yl-ethanone (CAS 83259-37-4)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
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