4,7-Dimethyl-8-phenylpyrazolo[5,1-c][1,2,4]triazine-3-carbohydrazide CAS 1374509-58-6
| CAS No. | 1374509-58-6 |
| Molecular Formula | C14H14N6O |
| Molecular Weight | 282.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,7-Dimethyl-8-phenylpyrazolo[5,1-c][1,2,4]triazine-3-carbohydrazide (CAS 1374509-58-6) is a high-purity analytical reference standard with the molecular formula C14H14N6O and a molecular weight of 282.30 g/mol.
The molecular framework of 4,7-Dimethyl-8-phenylpyrazolo[5,1-c][1,2,4]triazine-3-carbohydrazide (C14H14N6O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,7-Dimethyl-8-phenylpyrazolo[5,1-c][1,2,4]triazine-3-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14N6O |
| Molecular Weight | 282.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 6 |
Related Dimethyl Standards
- Methyl 1,3-dimethyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011397-76-4)
- 1',3'-dimethyl-1-phenyl-1H,1'H-3,4'-bipyrazole-4-carboxylic acid (CAS 956961-09-4)
- 3',5'-Dimethyl-1'-phenyl-1'h,2h-[3,4'-bipyrazole]-5-carboxylic acid (CAS 890007-02-0)
- 6-(3,5-Dimethyl-1H-pyrazol-1-yl)-N-(pyridin-4-ylmethyl)-1,2,4,5-tetrazin-3-amine (CAS 318239-49-5)
- 9,9-Dimethyl-9H-fluorene-2,7-dicarboxylic acid (CAS 690272-91-4)
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- Ethyl 2-((5,6-dimethyl-7-oxo-7,8-dihydro-[1,2,4]triazolo[4,3-a]pyrimidin-3-yl)thio)acetate (CAS 891133-42-9)
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Recommended Standards
- tert-Butyl (1s,3s)-3-(4-nitro-1H-imidazol-1-yl)cyclobutylcarbamate (CAS 1364663-31-9)
- 1-Methyl-5-[(2-methylpropan-2-yl)oxycarbonyl]-6,7-dihydro-4H-triazolo[4,5-c]pyridine-7-carboxylic acid (CAS 1391733-57-5)
- tert-Butyl (1r,3r)-3-(4-nitro-1H-imidazol-1-yl)cyclobutylcarbamate (CAS 1364663-24-0)
- 2-(1H-Indol-1-yl)-N-(6-methoxypyrimidin-4-yl)acetamide (CAS 1396767-99-9)
- methyl 3-amino-2-[(E)-2-cyanovinyl]-5-fluoro-benzoate (CAS 2765851-85-0)
- 6-chloro-N4-methyl-pyridazine-3,4-diamine (CAS 17645-09-9)
- 4-(1,3-Dioxolan-2-yl)-4-methylhexan-1-amine (CAS 1354952-43-4)
- 2-(3-Bromoquinolin-6-yl)acetic acid (CAS 1022091-93-5)
- 2-Amino-N-(2-oxopiperidin-3-yl)benzamide hydrochloride (CAS 1826099-06-2)
- Ethyl 6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-carboxylate (CAS 1173003-60-5)
- Ethyl 4-bromo-6-ethylquinoline-3-carboxylate (CAS 1242260-59-8)
- Ethyl 2-cyano-3-(1H-indazol-3-ylamino)acrylate (CAS 1858264-22-8)
- 4-[(phenylamino)methyl]phenol hydrochloride (CAS 6337-84-4)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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