4,4'-((3R,4S)-7-Hydroxy-8-methylchroman-3,4-diyl)diphenol CAS 1374524-68-1
| CAS No. | 1374524-68-1 |
| Molecular Formula | C22H20O4 |
| Molecular Weight | 348.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4,4'-((3R,4S)-7-Hydroxy-8-methylchroman-3,4-diyl)diphenol (CAS 1374524-68-1) is a high-purity analytical reference standard with the molecular formula C22H20O4 and a molecular weight of 348.39 g/mol.
Based on its molecular formula C22H20O4, 4,4'-((3R,4S)-7-Hydroxy-8-methylchroman-3,4-diyl)diphenol contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 348.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H20O4 |
| Molecular Weight | 348.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
Recommended Standards
- tert-Butyl 3-((R)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamido)pyrrolidine-1-carboxylate (CAS 1354025-31-2)
- 7-Phenyl-6,8-dioxa-spiro[3.5]nonane-2,2-dicarboxylic acid diethyl ester (CAS 142733-60-6)
- Tert-butyl 4-(2-(benzo[d][1,3]dioxol-5-yl)-2-oxoethyl)piperazine-1-carboxylate (CAS 1338676-41-7)
- Benzyl 4-((2-ethoxy-2-oxoethyl)carbamoyl)piperidine-1-carboxylate (CAS 147635-30-1)
- 2-Amino-N-(4-chlorophenyl)thiophene-3-carboxamide (CAS 590351-14-7)
- 2-Nitro-4-(pyrazin-2-ylthio)aniline (CAS 55564-29-9)
- Lofexidine D4 HCl (CAS 1206845-57-9)
- 2,5-Dichloro-3-fluorobenzyl bromide (CAS 1803784-30-6)
- 6-Fluoro-5-nitro-1H-indazole (CAS 633327-51-2)
- Tert-butyl (s)-(1-(4-bromobenzyl)pyrrolidin-3-yl)carbamate (CAS 1286208-27-2)
- 9,10-Anthracenedione, 1,4-bis[(4-butylphenyl)amino]-5,8-dihydroxy- (CAS 28198-05-2)
- 1-(Tert-butoxycarbonyl)-4-(pyridin-3-ylmethyl)piperidine-4-carboxylic acid (CAS 1695428-18-2)
- 3-Amino-4-chloro-5-(trifluoromethyl)benzoic acid (CAS 1805446-41-6)
- Dulaglutide (CAS 923950-08-7)
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