Tert-butyl (4-(aminomethyl)-4-fluorocyclohexyl)carbamate CAS 1374654-53-1
| CAS No. | 1374654-53-1 |
| Molecular Formula | C12H23FN2O2 |
| Molecular Weight | 246.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 246.32 g/mol gives Tert-butyl (4-(aminomethyl)-4-fluorocyclohexyl)carbamate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tert-butyl (4-(aminomethyl)-4-fluorocyclohexyl)carbamate (CAS 1374654-53-1) is a high-purity analytical reference standard with the molecular formula C12H23FN2O2 and a molecular weight of 246.32 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, Tert-butyl (4-(aminomethyl)-4-fluorocyclohexyl)carbamate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H23FN2O2 |
| Molecular Weight | 246.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
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