Piperidine-2,5-dicarbonitrile hydrochloride CAS 1374656-48-0
| CAS No. | 1374656-48-0 |
| Molecular Formula | C7H9N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 171.63 g/mol gives Piperidine-2,5-dicarbonitrile hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Piperidine-2,5-dicarbonitrile hydrochloride (CAS 1374656-48-0), a certified reference material (molecular formula C7H9N3HCl, MW 171.63 g/mol) for analytical method development and quality control.
The molecular framework of Piperidine-2,5-dicarbonitrile hydrochloride (C7H9N3HCl) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Piperidine-2,5-dicarbonitrile hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9N3 HCl |
| Molecular Weight | 171.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Piperidine Standards
- Piperidine-2,2,6,6-d4 (CAS 1001337-60-5)
- 2-Methyl-5-(piperidine-1-sulfonyl)benzene-1-sulfonyl chloride (CAS 100141-83-1)
- 2-Methyl-5-(piperidine-1-sulfonyl)-phenylamine (CAS 100317-20-2)
- Piperidine-1-carboximidamide xsulfate (CAS 100417-03-6)
- 1-(Piperidine-2-carbonyl)piperidine-4-carboxamide (CAS 1008079-89-7)
- Piperidine-3-sulfonamide (CAS 1016811-80-5)
- 1-(4-(Piperidine-4-carbonyl)piperazin-1-yl)ethanone (CAS 1016829-93-8)
- PIPERIDINE-3-CARBOXAMIDE HCL (CAS 1019852-04-0)
Recommended Standards
- Di(9H-fluoren-9-yl)dimethylsilane (CAS 18769-00-1)
- Ethyl 5-amino-2,3-dihydro-1H-indene-2-carboxylate (CAS 1616596-20-3)
- 6-Chloro-N-(2-(2-methyl-1H-imidazol-1-yl)ethyl)benzo[d]thiazol-2-amine (CAS 1219914-58-5)
- N-Methyl-N-phenylacridin-9-amine (CAS 90072-82-5)
- 4-Methyl-N-(4-(trifluoromethyl)phenyl)aniline (CAS 88429-26-9)
- 2-(2,4,5-Trichlorophenoxy)acetohydrazide (CAS 2381-77-3)
- Difelikefalin Impurity 87 (CAS CATO-C4X-304187)
- (R)-2-((1-Methylpiperidin-3-yl)amino)acetic acid (CAS 1354008-82-4)
- (1-(4-Isopropylphenyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1251230-05-3)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
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