(R)-2-Acetamido-3-(4-(benzyloxy)-3-fluorophenyl)propanoic acid CAS 1374669-65-4
| CAS No. | 1374669-65-4 |
| Molecular Formula | C18H18FNO4 |
| Molecular Weight | 331.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-2-Acetamido-3-(4-(benzyloxy)-3-fluorophenyl)propanoic acid (CAS 1374669-65-4), molecular formula C18H18FNO4 and molecular weight 331.34 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (R)-2-Acetamido-3-(4-(benzyloxy)-3-fluorophenyl)propanoic acid (C18H18FNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (R)-2-Acetamido-3-(4-(benzyloxy)-3-fluorophenyl)propanoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18FNO4 |
| Molecular Weight | 331.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 2-Acetamido-3-(4-(benzyloxy)-3-fluorophenyl)propanoic acid (CAS 1374651-36-1)
- 4-Acetamido-N-(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)benzamide (CAS 73623-32-2)
- Ethyl 2-acetamido-5-acetyl-4-phenylthiophene-3-carboxylate (CAS 333776-31-1)
- 5-Acetamido-2-methoxybenzene-1-sulfonyl fluoride (CAS 781-88-4)
- Methyl 4-acetamido-3-(4-chlorobenzoyl)benzoate (CAS 1309448-74-5)
- 7-Acetamido-d3 Clonazepam (1.0mg/ml in Acetonitrile) (CAS 1330166-04-5)
- Ethyl 2-acetamido-3-oxo-3-((3-(trifluoromethyl)phenyl)amino)propanoate (CAS 866017-96-1)
- N-(2'-Acetamido-[1,1'-biphenyl]-4-yl)benzamide (CAS 2203952-44-5)
Recommended Standards
- Methyl N-((benzyloxy)carbonyl)-O-(methylsulfonyl)serinate (CAS 1396968-11-8)
- N-Benzyloxycarbonyl-O-mesyl-L-serine methyl ester (CAS 132249-34-4)
- N-(3-(3-Fluorophenyl)-2-(2-oxoimidazolidin-1-yl)propyl)furan-2-carboxamide (CAS 1421513-66-7)
- 2-(1,3-Dioxoisoindolin-2-yl)ethyl benzenesulfonate (CAS 13031-58-8)
- [(2,3-Dimethoxyphenyl)methyl](prop-2-en-1-yl)amine (CAS 849000-01-7)
- 4-Methoxyphenyl (3Z)-3-{[(2,6-dichlorophenyl)methoxy]imino}propanoate (CAS 338404-03-8)
- 6-Bromo-1-methyl-1H-benzo[c][1,2]thiazin-4(3H)-one 2,2-dioxide (CAS 13568-96-2)
- 3-Chloro-6-methylbenzo[b]thiophene-2-carboxamide (CAS 34586-87-3)
- tert-Butyl 3-(2,2,2-trifluoro-1-hydroxyethyl)azetidine-1-carboxylate (CAS 1628733-94-7)
- 1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 131776-00-6)
- Alinidine (CAS 33178-86-8)
- Methyl 3-amino-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylate hydrochloride (CAS 1984136-54-0)
- Methyl 4-cyano-2-hydroxybenzoate (CAS 188793-06-8)
- Semaglutide (CAS CATO-C4X-2226105)
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