Trilaciclib Impurity 1 CAS 1374743-01-7
| CAS No. | 1374743-01-7 |
| Molecular Formula | C23H28N8O |
| Molecular Weight | 432.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Trilaciclib Impurity 1 (CAS 1374743-01-7), a pharmacopoeial impurity reference standard (molecular formula C23H28N8O, MW 432.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Trilaciclib Impurity 1 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Trilaciclib Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H28N8O |
| Molecular Weight | 432.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 8 |
Related Trilaciclib Standards
- Trilaciclib (CAS 1374743-00-6)
- Trilaciclib impurity 15 (CAS CATO-C4X-304415)
- Trilaciclib Impurity 2 (CAS CATO-C4X-30442)
- Trilaciclib Impurity 11 (CAS 2170746-99-1)
- Trilaciclib Impurity 16 (CAS CATO-C4X-304416)
- Trilaciclib Impurity 13 (CAS CATO-C4X-304413)
- Trilaciclib Impurity 14 (CAS CATO-C4X-304414)
- Trilaciclib Impurity 5 (CAS CATO-C4X-30445)
Recommended Standards
- Erdafitinib Impurity 11 (CAS 1346243-54-6)
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- (1R)-1-(3,4-Dimethoxyphenyl)-4-hydroxy-2-cyclohexene-1-ethanol 1-(4-Methylbenzenesulfonate) (CAS 866394-50-5)
- Dalilesen impurity 38 (CAS 1505484-57-0)
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- (3-Acetyloxy-2-ethoxycarbonylbenzyl)-triphenylphosphonium bromide (CAS 118842-88-9)
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- 8-(3-Fluorophenoxy)imidazo[1,2-a]pyrazine-6-carboximidamide hydrochloride (CAS 2052362-59-9)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com