3′-Carboxy-4′-fluoro[1,1′-biphenyl]-3-acetic acid CAS 1375068-82-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1375068-82-8
Molecular FormulaC15H11FO4
Molecular Weight274.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3′-Carboxy-4′-fluoro[1,1′-biphenyl]-3-acetic acid CAS 1375068-82-8 chemical structure

Description

3′-Carboxy-4′-fluoro[1,1′-biphenyl]-3-acetic acid (CAS 1375068-82-8) is a high-purity analytical reference standard with the molecular formula C15H11FO4 and a molecular weight of 274.24 g/mol.

The molecular framework of 3′-Carboxy-4′-fluoro[1,1′-biphenyl]-3-acetic acid (C15H11FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3′-Carboxy-4′-fluoro[1,1′-biphenyl]-3-acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H11FO4
Molecular Weight274.24 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF-containing

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