3-Bromo-5-(2,2,2-trifluoroethyl)pyridine CAS 1375303-72-2
| CAS No. | 1375303-72-2 |
| Molecular Formula | C7H5BrF3N |
| Molecular Weight | 240.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Bromo-5-(2,2,2-trifluoroethyl)pyridine (C7H5BrF3N) is characterized by a nitrile group, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-Bromo-5-(2,2,2-trifluoroethyl)pyridine (CAS 1375303-72-2), molecular formula C7H5BrF3N and molecular weight 240.02 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-5-(2,2,2-trifluoroethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BrF3N |
| Molecular Weight | 240.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-4-methyl-2-(trifluoromethyl)pyridine (CAS 1010422-51-1)
- 5-Bromo-3-methyl-2-(trifluoromethyl)pyridine (CAS 1010422-52-2)
- 3-Bromo-2-methyl-6-(trifluoromethyl)pyridine (CAS 1010422-53-3)
- 3-Bromo-6-methyl-2-(trifluoromethyl)pyridine (CAS 1211517-98-4)
- 3-Bromo-4-methyl-5-(trifluoromethyl)pyridine (CAS 1211518-50-1)
- 2-bromo-3-methyl-5-(trifluoromethyl)pyridine (CAS 1211520-05-6)
- 2-Bromo-3-methyl-6-(trifluoromethyl)pyridine (CAS 1211525-93-7)
- 5-Bromo-2-methyl-3-(trifluoromethyl)pyridine (CAS 1211526-51-0)
Recommended Standards
- 2-Bromo-5-(2,2,2-trifluoroethyl)pyridine (CAS 1346531-45-0)
- 1-Ethyl-5-fluoro-4-iodo-1H-pyrazole (CAS 1392274-31-5)
- 5-Bromo-2-(2,2,2-trifluoroethyl)pyridine (CAS 1335050-19-5)
- 5-Fluoro-4-iodo-1,3-dimethyl-1H-pyrazole (CAS 1392274-43-9)
- tert-Butyl 2,6-diazaspiro[3.4]octane-6-carboxylate oxalate(2:1) (CAS 1523618-25-8)
- 4-Chloro-2-methoxy-5-methylphenyl isocyanide (CAS 1930-96-7)
- 4-Iodo-5-methyl-3-nitro-1H-pyrazole (CAS 1281872-29-4)
- 7-cyano-1H-indole-2-carboxylic acid (CAS 796870-32-1)
- 7-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroisoquinolin-1(2H)-one (CAS 2857092-80-7)
- 3,5-Dichloro-4-fluorobenzaldehyde (CAS 117820-80-1)
- 5-Amino-1-(3-ethoxypropyl)pyrimidine-2,4(1h,3h)-dione (CAS 1468936-13-1)
- [(4-Allyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio]-acetic acid (CAS 18204-57-4)
- 2-{[(4-methoxyphenyl)methyl]sulfanyl}-5-[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]-1,3,4-oxadiazole (CAS 477709-80-1)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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