1-(2-Chlorobenzoyl)piperazine CAS 13754-45-5
| CAS No. | 13754-45-5 |
| Molecular Formula | C11H13ClN2O |
| Molecular Weight | 224.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2-Chlorobenzoyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(2-Chlorobenzoyl)piperazine (CAS 13754-45-5) is a high-purity analytical reference standard with the molecular formula C11H13ClN2O and a molecular weight of 224.69 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-(2-Chlorobenzoyl)piperazine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 224.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13ClN2O |
| Molecular Weight | 224.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzoyl Standards
- 1-(4-Chlorobenzoyl)piperazine (CAS 54042-47-6)
- 4-(4-Chlorobenzoyl)oxane (CAS 1344053-12-8)
- 1-(2-Chlorobenzoyl)pyrazolidin-3-one (CAS 477850-56-9)
- 1-(4-Chlorobenzoyl)pyrazolidin-3-one (CAS 477850-54-7)
- 4-(3-Chlorobenzoyl)morpholine (CAS 26162-86-7)
- Ethyl (2-chlorobenzoyl)acetate (CAS 19112-35-7)
- Ethyl (3-Chlorobenzoyl)acetate (CAS 33167-21-4)
- 5-(2-Chlorobenzoyl)-2-methyl-2H-1,2,3,4-tetrazole (CAS 1858599-02-6)
Recommended Standards
- 5-chloro-2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)aniline (CAS 1361968-02-6)
- 4-Chloro-7-methyl-N-propyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine (CAS 1380343-09-8)
- 2-(6-Chloro-5-methylpyridin-3-yl)pyrrolidine-1-carbaldehyde (CAS 1352534-52-1)
- 7-Chloro-3-ethyl-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one (CAS 1447607-27-3)
- Methyl 2-amino-4-(4-methoxyphenyl)thiophene-3-carboxylate (CAS 350988-34-0)
- 3-(tert-Butyl)-1-(heptan-2-yl)-1H-pyrazol-5(4H)-one (CAS 864685-48-3)
- 2-[Chloro(difluoro)methoxy]-1,3,4-trifluoro-benzene (CAS 1404193-81-2)
- 1-Ethylindolin-6-amine (CAS 143543-67-3)
- Methyl 1-(piperidin-4-yl)pyrrolidine-3-carboxylate (CAS 939900-28-4)
- 2-Bromo-5-chloro-6-methylnicotinonitrile (CAS 1414959-00-4)
- 5,6-Di(pyridin-2-yl)-2,3-dihydropyrazine (CAS 25005-95-2)
- 5beta-Dutasteride (CAS 957229-52-6)
- Methyl 2-(3-(4-nitrophenyl)thioureido)thiophene-3-carboxylate (CAS 338777-35-8)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
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