Methyl 2-(3-bromo-2-oxopyrrolidin-1-yl)thiophene-3-carboxylate CAS 1375471-71-8

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Methyl 2-(3-bromo-2-oxopyrrolidin-1-yl)thiophene-3-carboxylate (CAS 1375471-71-8), molecular formula C10H10BrNO3S and molecular weight 304.16 g/mol, is a CATO reference standard with documented purity and traceability.

Methyl 2-(3-bromo-2-oxopyrrolidin-1-yl)thiophene-3-carboxylate (C10H10BrNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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