[2-(trifluoromethyl)cyclohexyl]methanamine CAS 1375473-80-5

Description

Compared with other compounds in its class, the molecular weight of 181.20 g/mol gives [2-(trifluoromethyl)cyclohexyl]methanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

[2-(trifluoromethyl)cyclohexyl]methanamine (CAS 1375473-80-5) is a high-purity analytical reference standard with the molecular formula C8H14F3N and a molecular weight of 181.20 g/mol.

The molecular framework of [2-(trifluoromethyl)cyclohexyl]methanamine (C8H14F3N) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), [2-(trifluoromethyl)cyclohexyl]methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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