6-Amino-3-nitro-6,7,8,9-tetrahydro-11h-pyrido[2,1-b]quinazolin-11-one CAS 1375474-01-3
| CAS No. | 1375474-01-3 |
| Molecular Formula | C12H12N4O3 |
| Molecular Weight | 260.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 6-Amino-3-nitro-6,7,8,9-tetrahydro-11h-pyrido[2,1-b]quinazolin-11-one (CAS 1375474-01-3), a certified reference material (molecular formula C12H12N4O3, MW 260.25 g/mol) for analytical method development and quality control.
6-Amino-3-nitro-6,7,8,9-tetrahydro-11h-pyrido[2,1-b]quinazolin-11-one (C12H12N4O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H12N4O3 |
| Molecular Weight | 260.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 2-Amino-3-carbamoyl-5-(4-methoxyphenyl)pyrazine 1-oxide (CAS 113120-68-6)
- 6-Amino-9-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine-2-carbonitrile (CAS 122970-25-6)
- Methyl 2-amino-1-benzoyl-4-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate (CAS 1255147-39-7)
- ethyl 5-amino-6-oxo-1-phenyl-1,6-dihydro-1,2,4-triazine-3-carboxylate (CAS 127720-99-4)
- 6-Amino-2-nitro-6,7,8,9-tetrahydro-11H-pyrido[2,1-b]quinazolin-11-one (CAS 1375473-99-6)
- 5-Amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazole-4-carboxamide (CAS 1416348-13-4)
- N-(6-Amino-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)benzamide (CAS 167299-05-0)
- 2-[(5-amino-1-phenyl-1h-pyrazol-4-yl)formamido]acetic acid (CAS 956191-91-6)
Recommended Standards
- 5-(Allyloxy)-1-carbamoyl-1H-indole-3-carboxylic acid (CAS 1386456-36-5)
- 1-[4-(Trifluoromethoxy)phenyl]hexan-1-one (CAS 1365271-68-6)
- (3ar,4s,9bS)-8-nitro-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid (CAS 1415811-49-2)
- 5-(Benzyloxy)-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid (CAS 1338091-25-0)
- 4-(5-Nitro-1H-indazol-3-yl)morpholine (CAS 67400-26-4)
- 2-(Pyridin-4-yl)-[1,2,4]triazolo[1,5-a]pyridine-8-carboxylic acid (CAS 919990-85-5)
- N-(4-(4-Ethylpiperazin-1-yl)phenyl)quinolin-4-amine (CAS 313494-81-4)
- N-(2-Bromo-5-formylpyridin-3-yl)pivalamide (CAS 1142192-34-4)
- 4-Chloro-1-(2-fluoro-ethyl)-1h-pyrazol-3-ylamine (CAS 1427023-63-9)
- 2-Fluoro-n-methylbenzamide (CAS 52833-63-3)
- 2-({tricyclo[5.2.1.0²,⁶]decan-8-yl}amino)propan-1-ol (CAS 1218624-73-7)
- methyl 1-cyclohexylazetidine-2-carboxylate (CAS 18085-36-4)
- (R)-N-(Naphthalen-2-ylmethyl)-2-(9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)ethanamine (CAS 1401030-95-2)
- (2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine (2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine 2-Amino-4-(methylphosphino)butyrylalanylalanine 35597-43-4 Antibiotic SF 1293 Bialaphos CHEBI:3088 L-phosphinothricyl-L-alanyl-L-alanine N-{(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl}-L-alanyl-L-alanine PTT Phosphinothricylalanylalanine bilanafos gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine phosphinothricin tripeptide (CAS 35597-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com