3-Bromo-8-methyl-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one CAS 1375474-08-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1375474-08-0
Molecular FormulaC12H11BrN2O
Molecular Weight279.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Bromo-8-methyl-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one CAS 1375474-08-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 279.13 g/mol gives 3-Bromo-8-methyl-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-Bromo-8-methyl-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one (CAS 1375474-08-0), molecular formula C12H11BrN2O and molecular weight 279.13 g/mol, is a CATO reference standard with documented purity and traceability.

3-Bromo-8-methyl-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one (C12H11BrN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H11BrN2O
Molecular Weight279.13 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentBr-containing
Nitrogen Atoms2

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