3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride CAS 1375474-26-2
| CAS No. | 1375474-26-2 |
| Molecular Formula | C10H15N3O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride (C10H15N3OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
3-(5-Cyclopropyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride (CAS 1375474-26-2), molecular formula C10H15N3OHCl and molecular weight 229.71 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15N3O HCl |
| Molecular Weight | 229.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- 4-(Difluoromethyl)-2-(methylthio)benzo[d]oxazole (CAS 1806321-23-2)
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- n-((1,2,3-Thiadiazol-4-yl)methyl)-2,4,4-trimethylpentan-2-amine (CAS 1157983-38-4)
- Liraglutide Impurity 21 TFA Salt (CAS CATO-C4X-199221)
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