3-Bromo-6-nitro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one CAS 1375474-48-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1375474-48-8
Molecular FormulaC11H8BrN3O3
Molecular Weight310.10 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Bromo-6-nitro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one CAS 1375474-48-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 310.10 g/mol gives 3-Bromo-6-nitro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

3-Bromo-6-nitro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one (CAS 1375474-48-8), molecular formula C11H8BrN3O3 and molecular weight 310.10 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C11H8BrN3O3, 3-Bromo-6-nitro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 310.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Bromo-6-nitro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1h)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8BrN3O3
Molecular Weight310.10 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentBr-containing
Nitrogen Atoms3

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