3-Amino-7-fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one CAS 1375474-72-8
| CAS No. | 1375474-72-8 |
| Molecular Formula | C11H10FN3O |
| Molecular Weight | 219.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-Amino-7-fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 3-Amino-7-fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one (CAS 1375474-72-8), a certified reference material (molecular formula C11H10FN3O, MW 219.22 g/mol) for analytical method development and quality control.
The molecular framework of 3-Amino-7-fluoro-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one (C11H10FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10FN3O |
| Molecular Weight | 219.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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