2-((2-Amino-6-chloropyrimidin-4-yl)(methyl)amino)-N-isopropylacetamide CAS 1376004-99-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1376004-99-7
Molecular FormulaC10H16ClN5O
Molecular Weight257.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((2-Amino-6-chloropyrimidin-4-yl)(methyl)amino)-N-isopropylacetamide CAS 1376004-99-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((2-Amino-6-chloropyrimidin-4-yl)(methyl)amino)-N-isopropylacetamide.

2-((2-Amino-6-chloropyrimidin-4-yl)(methyl)amino)-N-isopropylacetamide (CAS 1376004-99-7) is a high-purity analytical reference standard with the molecular formula C10H16ClN5O and a molecular weight of 257.72 g/mol.

2-((2-Amino-6-chloropyrimidin-4-yl)(methyl)amino)-N-isopropylacetamide (C10H16ClN5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H16ClN5O
Molecular Weight257.72 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl-containing
Nitrogen Atoms5

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