2-Chloro-6-methoxyquinoline-3-carboxylic acid CAS 137612-85-2
| CAS No. | 137612-85-2 |
| Molecular Formula | C11H8ClNO3 |
| Molecular Weight | 237.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-6-methoxyquinoline-3-carboxylic acid.
2-Chloro-6-methoxyquinoline-3-carboxylic acid (CAS 137612-85-2) is a high-purity analytical reference standard with the molecular formula C11H8ClNO3 and a molecular weight of 237.64 g/mol.
Structurally, 2-Chloro-6-methoxyquinoline-3-carboxylic acid (C11H8ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 237.64 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO3 |
| Molecular Weight | 237.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-5-cyclopropylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1011354-08-7)
- 2-Chloro-8-methoxyquinoline-3-carboxylic acid (CAS 1017157-83-3)
- 6-Chloro-4-hydroxy-2-methylquinoline-3-carboxylic acid (CAS 103566-34-3)
- 1-(3-Chloro-2-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042534-76-8)
- 1-(3-Chloro-4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1042604-53-4)
- 2-Chloro-6-hydroxy-7-methoxyquinoline-3-carbaldehyde (CAS 1046138-52-6)
- Methyl 8-chloro-4-hydroxyquinoline-2-carboxylate (CAS 1065074-57-8)
- 2-(8-Chloro-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1092288-62-4)
Recommended Standards
- Methyl 6-chloro-4-hydroxyquinoline-2-carboxylate (CAS 1373835-05-2)
- 2-Acetyl-6-fluoropyridine-4-sulfonyl chloride (CAS 1393531-32-2)
- 2-(4-Chlorobenzyl)oxazole-4-carboxylic Acid (CAS 1368958-26-2)
- 6-Acetyl-4-fluoropyridine-2-sulfonyl chloride (CAS 1393545-35-1)
- 2-(2-(Benzo[b]thiophen-2-yl)vinyl)quinoline (CAS 133610-12-5)
- Levodropropizine Impurity 13 (CAS 1095540-43-4)
- Ethyl 2-(methylthio)-4-(3-oxo-1,4-diazaspiro[5.5]undecan-1-yl)pyrimidine-5-carboxylate (CAS 2170746-95-7)
- Ethyl N-(ethoxycarbonyl)-N-(3-iodo-5-nitropyridin-2-yl)carbamate (CAS 1971131-38-0)
- (S)-9a-(4-bromophenyl)-8-phenyl-9,9a-dihydropyrido[1,2-a]indole-6,10-dione (CAS 2368852-03-1)
- {5-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine (CAS 1368189-28-9)
- 3-(Dimethylamino)phenyl acetate (CAS 17579-36-1)
- 6-Bromo-1H-pyrrolo[2,3-b]pyridine-3-sulfonyl chloride (CAS 2231234-27-6)
- 6-Bromo-4-(dibromomethyl)-5,5-dimethyl-N-(pyridin-2-yl)bicyclo[2.1.1]Hexane-1-carboxamide (CAS 256954-40-2)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com