4-(4-Fluorophenoxy)benzaldehyde CAS 137736-06-2
| CAS No. | 137736-06-2 |
| Molecular Formula | C13H9FO2 |
| Molecular Weight | 216.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-Fluorophenoxy)benzaldehyde (C13H9FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(4-Fluorophenoxy)benzaldehyde (CAS 137736-06-2) is a high-purity analytical reference standard with the molecular formula C13H9FO2 and a molecular weight of 216.21 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(4-Fluorophenoxy)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9FO2 |
| Molecular Weight | 216.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
Related Fluorophenoxy Standards
- 2-(3-Fluorophenoxy)benzaldehyde (CAS 1020931-53-6)
- 2-(2-Fluorophenoxy)benzaldehyde (CAS 82097-82-3)
- 2-(4-Fluorophenoxy)benzaldehyde (CAS 320423-61-8)
- 3-(4-Fluorophenoxy)benzaldehyde (CAS 65295-61-6)
- 4-(2-Fluorophenoxy)benzaldehyde (CAS 936343-96-3)
- 4-(3-Fluorophenoxy)benzaldehyde (CAS 939758-29-9)
- 2-(4-Fluorophenoxy)butanoyl chloride (CAS 1160257-66-8)
- 2-(2-Ethyl-4-fluorophenoxy)acetyl chloride (CAS 1987321-02-7)
Recommended Standards
- (E)-3-(4-Fluorophenyl)-1-(furan-2-yl)prop-2-en-1-one (CAS 135950-64-0)
- 5-Amino-1-(3-fluoro-4-methylphenyl)-1H-pyrazole-4-carbonitrile (CAS 1416344-54-1)
- 5-(3-Fluorophenyl)nicotinamide (CAS 1356110-53-6)
- (2E)-3-(4-fluoronaphthalen-1-yl)prop-2-enoic acid (CAS 1453089-75-2)
- 3-Bromo-6-chloroisobenzofuran-1(3H)-one (CAS 40125-48-2)
- Methylmalonic acid (dipotassium) (CAS 77939-79-8)
- 2-{[4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl]-thio}propanoic acid (CAS 505054-76-2)
- Imipramine 2-Hydroxy β-D-Glucuronide (CAS 54190-76-0)
- 2,5-Difluoro-3-(naphthalen-2-yl)-5-phenyl-4H,5H,6H,7H-thieno[2,3-b]pyridine-4,6-dione (CAS 1313504-21-0)
- methyl 4-(cyanocarbamoyl)benzoate (CAS 2044713-02-0)
- 6-(Azetidin-1-yl)-5-bromopyridin-3-amine (CAS 1855655-10-5)
- 2-[[1-(1H-Benzimidazol-2-yl)ethyl]thio]acetic acid (CAS 790270-73-4)
- 3-((Pyridin-4-ylmethyl)amino)propanoic acid dihydrochloride (CAS 1171101-21-5)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com