Ethyl 4-bromo-7-chloroquinoline-3-carboxylate CAS 1378259-43-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1378259-43-8
Molecular FormulaC12H9BrClNO2
Molecular Weight314.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 4-bromo-7-chloroquinoline-3-carboxylate CAS 1378259-43-8 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Ethyl 4-bromo-7-chloroquinoline-3-carboxylate (CAS 1378259-43-8), molecular formula C12H9BrClNO2 and molecular weight 314.56 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C12H9BrClNO2, Ethyl 4-bromo-7-chloroquinoline-3-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 314.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

CATO manufactures Ethyl 4-bromo-7-chloroquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H9BrClNO2
Molecular Weight314.56 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentCl/Br-containing
Nitrogen Atoms1

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