4-Bromo-6-fluoro-2,8-dimethylquinoline CAS 1378259-56-3
| CAS No. | 1378259-56-3 |
| Molecular Formula | C11H9BrFN |
| Molecular Weight | 254.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-6-fluoro-2,8-dimethylquinoline (CAS 1378259-56-3) is a high-purity analytical reference standard with the molecular formula C11H9BrFN and a molecular weight of 254.10 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution, 4-Bromo-6-fluoro-2,8-dimethylquinoline is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 254.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Bromo-6-fluoro-2,8-dimethylquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9BrFN |
| Molecular Weight | 254.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 1-(2-Bromo-4-fluorophenyl)cyclobutanecarbonitrile (CAS 1086599-29-2)
- 8-Bromo-5-fluoro-2,4-dimethylquinoline (CAS 1227293-43-7)
- 2-Bromo-N,N-dimethyl-1H-imidazole-1-sulfonamide (CAS 1239205-21-0)
- 1-(4-Bromo-3-fluorophenyl)cyclobutanecarbonitrile (CAS 1314703-96-2)
- 1-(5-Bromo-2-fluorophenyl)cyclobutanecarbonitrile (CAS 1314756-43-8)
- 4-Bromo-5-fluoro-2,8-dimethylquinoline (CAS 1378260-91-3)
- 8-Bromo-6-fluoro-2,5-dimethylquinoline (CAS 1420790-86-8)
- 8-Bromo-6-fluoro-2,7-dimethylquinoline (CAS 1420793-57-2)
Recommended Standards
- 5-Bromo-8-fluoro-2,6-dimethylquinoline (CAS 1420793-59-4)
- 8-Bromo-6-fluoro-4,7-dimethylquinoline (CAS 1420794-00-8)
- Indapamide Impurity 21 (CAS 70049-77-3)
- 5-Bromo-6-fluoro-2,8-dimethylquinoline (CAS 1420794-11-1)
- 2,2'-(thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one) (CAS 1688656-86-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com