4-(Methoxycarbonyl)-5-(trifluoromethyl)furan-3-carboxylic acid CAS 1378259-63-2
| CAS No. | 1378259-63-2 |
| Molecular Formula | C8H5F3O5 |
| Molecular Weight | 238.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Methoxycarbonyl)-5-(trifluoromethyl)furan-3-carboxylic acid.
4-(Methoxycarbonyl)-5-(trifluoromethyl)furan-3-carboxylic acid (CAS 1378259-63-2), molecular formula C8H5F3O5 and molecular weight 238.12 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Methoxycarbonyl)-5-(trifluoromethyl)furan-3-carboxylic acid (C8H5F3O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5F3O5 |
| Molecular Weight | 238.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
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Recommended Standards
- 3-Bromo-5-(tert-butyl)benzonitrile (CAS 1369836-56-5)
- 6'-Bromospiro[cyclobutane-1,3'-indoline] (CAS 1379363-66-2)
- 4-Bromo-2-(tert-butyl)benzonitrile (CAS 1369819-64-6)
- 4-Bromo-2,6-dicyclopropylpyridine (CAS 1379368-18-9)
- 6-Iodobenzo[d]oxazol-2-amine (CAS 1804102-68-8)
- 2-(4-Amino-2-hydroxybenzamido)acetic Acid (CAS 7414-98-4)
- (2,5-Dimethylfuran-3-carbonyl)proline (CAS 496918-99-1)
- 3,5-Dimethoxy-N-methylaniline hydrochloride (CAS 1797132-05-8)
- 2-((2,3-Dimethylphenyl)amino)-N-(methylcarbamoyl)propanamide (CAS 1046269-91-3)
- 4-(4H-1,2,4-triazol-4-yl)pyridine (CAS 25700-21-4)
- 1-Benzyl-2,3-dihydro-1H-indol-5-amine (CAS 21909-45-5)
- 1-(2-Bromo-3-(trifluoromethoxy)phenyl)ethanone (CAS 1588441-04-6)
- 1-[4-(1-phenylethoxy)phenyl]ethan-1-amine hydrochloride (CAS 1955554-76-3)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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