2-Hydroxy-1H-benzo[d]imidazole-4-sulfonamide CAS 1378260-67-3
| CAS No. | 1378260-67-3 |
| Molecular Formula | C7H7N3O3S |
| Molecular Weight | 213.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-Hydroxy-1H-benzo[d]imidazole-4-sulfonamide (CAS 1378260-67-3), a certified reference material (molecular formula C7H7N3O3S, MW 213.21 g/mol) for analytical method development and quality control.
2-Hydroxy-1H-benzo[d]imidazole-4-sulfonamide (C7H7N3O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7N3O3S |
| Molecular Weight | 213.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 9-Amino-6-oxa-2-thiaspiro[4.5]decane 2,2-dioxide (CAS 1341311-12-3)
- 2-Amino-6-(difluoromethyl)-4-methoxypyridin-3-ol (CAS 1805137-56-7)
- 2-Methyl-1,2,3,4-tetrahydroisoquinolin-8-ol (CAS 14788-32-0)
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- (6-(9,9-Dihexyl-9H-fluoren-2-yl)pyridin-3-yl)methanol (CAS 921754-95-2)
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