3-Chloro-2-(methylthio)-5-(trifluoromethyl)pyridine CAS 1378308-91-8
| CAS No. | 1378308-91-8 |
| Molecular Formula | C7H5ClF3NS |
| Molecular Weight | 227.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Chloro-2-(methylthio)-5-(trifluoromethyl)pyridine (CAS 1378308-91-8) is a high-purity analytical reference standard with the molecular formula C7H5ClF3NS and a molecular weight of 227.63 g/mol.
3-Chloro-2-(methylthio)-5-(trifluoromethyl)pyridine (C7H5ClF3NS) contains a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-Chloro-2-(methylthio)-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF3NS |
| Molecular Weight | 227.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-methyl-5-trifluoromethylsulfanylpyridine (CAS 1246466-87-4)
- (4-Chloro-3-fluorophenyl)(1h-1,2,3,4-tetrazol-5-yl)methanamine (CAS 1247472-41-8)
- 2-((1-Chloro-2,2,2-trifluoroethyl)thio)pyridine (CAS 145143-27-7)
- 2-Chloro-3-methylthio-6-(trifluoromethyl)pyridine (CAS 1809161-56-5)
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- 2-Chloro-5-((trifluoromethyl)thio)aniline (CAS 933674-81-8)
- 4-Chloro-3-propionamidobenzoic acid (CAS 1016698-05-7)
- 5-Chloro-6-(cyclopropylmethoxy)pyridine-3-carboxylic acid (CAS 1019493-16-3)
Recommended Standards
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- 5-Chloro-2-(p-tolyl)benzo[d]oxazole (CAS 16715-75-6)
- Methyl 5-(2-(methoxycarbonyl)phenyl)furan-2-carboxylate (CAS 1361151-68-9)
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- Bis(trifluoro-2,4-pentanedionato)magnesium(ii) dihydrate (CAS 240131-46-8)
- Cycloaspeptide A (CAS 109171-13-3)
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