Imidazo[1,2-a]pyrimidine-2-carbohydrazide CAS 1378345-44-8
| CAS No. | 1378345-44-8 |
| Molecular Formula | C7H7N5O |
| Molecular Weight | 177.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 177.16 g/mol gives Imidazo[1,2-a]pyrimidine-2-carbohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Imidazo[1,2-a]pyrimidine-2-carbohydrazide (CAS 1378345-44-8), molecular formula C7H7N5O and molecular weight 177.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Imidazo[1,2-a]pyrimidine-2-carbohydrazide (C7H7N5O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Imidazo[1,2-a]pyrimidine-2-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7N5O |
| Molecular Weight | 177.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 5 |
Related Imidazo Standards
- 2-(Imidazo[1,2-a]pyrazin-3-yl)acetic acid (CAS 1000565-73-0)
- 2-(3H-Imidazo[4,5-b]pyridin-2-yl)acetic acid (CAS 107932-99-0)
- Methyl imidazo[1,2-a]pyrimidine-6-carboxylate (CAS 1083196-24-0)
- methyl imidazo[1,2-a]pyrimidine-2-carboxylate (CAS 1119452-82-2)
- Methyl imidazo[1,2-a]pyrazine-3-carboxylate (CAS 1206983-57-4)
- Methyl Imidazo[1,2-b]pyridazine-6-carboxylate (CAS 1234616-21-7)
- Methyl imidazo[1,5-b]pyridazine-5-carboxylate (CAS 1403767-17-8)
- Methyl imidazo[1,2-a]pyrazine-6-carboxylate (CAS 1448536-57-9)
Recommended Standards
- 3-(Aminomethyl)-5-nitrobenzonitrile (CAS 1369916-24-4)
- methyl furo[3,2-b]pyridine-3-carboxylate (CAS 1378826-09-5)
- 2-Methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1369341-62-7)
- 4-Cyano-2-(hydroxymethyl)benzoic acid (CAS 1378843-02-7)
- Methyl (R)-3-amino-3-(3-chloro-4-methoxyphenyl)propanoate (CAS 1213395-90-4)
- 3-Chloro-5-(trifluoromethoxy)benzoic acid (CAS 433926-46-6)
- N,1-diphenylcyclopentane-1-carboxamide (CAS 328964-72-3)
- 1-(3-(Aminomethyl)phenyl)-2-(4-chlorophenyl)ethanone (CAS 1017781-65-5)
- 1-Chloro-4-(propan-2-yl)benzene (CAS 2621-46-7)
- 4-Methoxy-5-methylbenzene-1,2-diamine (CAS 38608-08-1)
- 2-(4-Chlorophenyl)-2-methyl-1,3-dioxolane (CAS 36881-02-4)
- 2-(3-Nitrophenyl)cyclopropane-1-carboxylic acid (CAS 91880-89-6)
- N-(3-chlorophenyl)-8-methyl-4H-thieno[3,2-c]thiochromene-2-carboxamide (CAS 477887-22-2)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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