Valsartan Impurity 14 CAS 137863-90-2
| CAS No. | 137863-90-2 |
| Molecular Formula | C25H30N2O3 |
| Molecular Weight | 406.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Valsartan Impurity 14 (CAS 137863-90-2) is a certified pharmaceutical impurity reference standard with the molecular formula C25H30N2O3 and a molecular weight of 406.52 g/mol.
Based on its molecular formula C25H30N2O3, Valsartan Impurity 14 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 406.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H30N2O3 |
| Molecular Weight | 406.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
Related Valsartan Standards
- Valsartan Impurity 116 (CAS CATO-C4X-1057116)
- Valsartan Impurity 61 (CAS 137862-57-8)
- Valsartan Impurity 84 (CAS CATO-C4X-105784)
- Valsartan Impurity 92 (CAS CATO-C4X-105792)
- Valsartan Impurity 129 (CAS CATO-C4X-1057129)
- Valsartan Impurity 137 (CAS CATO-C4X-1057137)
- Valsartan Impurity 138 (CAS CATO-C4X-1057138)
- Valsartan Impurity 111 (CAS CATO-C4X-1057111)
Recommended Standards
- 4-Cyano-N-(4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl)-1H-pyrrole-2-carboxamide 4406AC 885704-21-2 C23H30N6O (CAS 885704-21-2)
- Olaparib Impurity 165 (CAS CATO-C4X-1135165)
- tert-Butyl 4-(2-(6-((tert-butoxycarbonyl)amino)pyridin-3-yl)ethyl)piperazine-1-carboxylate (CAS 2602340-75-8)
- Rosuvastatin Impurity 112 (CAS CATO-C4X-1169112)
- Bortezomib Impurity 47（1S,2R） (CAS CATO-C4X-107247)
- Ilaprazole Impurity 100 (CAS CATO-C4X-1130100)
- Neratinib Impurity 16 (CAS 1376619-94-1)
- 1-(2-(Difluoromethyl)-5-fluorophenyl)ethan-1-one (CAS 1417506-86-5)
- Methyl 5-Bromo-2-(bromomethyl)benzoate (CAS 79670-17-0)
- Cyclohexane-1,2,3-triol (CAS 6286-43-7)
- (5E)-5-({2-[(4-methylphenyl)sulfanyl]-5-nitrophenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 286860-13-7)
- 2-benzoylbutanenitrile (CAS 7391-31-3)
- 3-(ethylsulfanyl)benzoic acid (CAS 5537-74-6)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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