Benzenemethanol, alpha-(chloromethyl)-3-hydroxy- CAS 1378757-22-2
| CAS No. | 1378757-22-2 |
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Benzenemethanol, alpha-(chloromethyl)-3-hydroxy- (C8H9ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Benzenemethanol, alpha-(chloromethyl)-3-hydroxy- (CAS 1378757-22-2), molecular formula C8H9ClO2 and molecular weight 172.61 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9ClO2 |
| Molecular Weight | 172.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
Related Benzenemethanol Standards
- 3391-10-4 Benzenemethanol, 4-chloro-alpha-methyl- Benzyl alcohol, p-chloro-alpha-methyl- (8CI) 4-Chloro-alpha-methylbenzyl alcohol AI3-02463 p-Chloro-alpha-methylbenzyl alcohol alpha-(p-Chlorophenyl)ethanol 1-(p-Chlorophenyl)ethanol 1-(4-Chlorophenyl)ethanol EINECS 222-223-4 NSC 87867 (CAS 3391-10-4)
- Benzenemethanol, a-(aminomethyl)-4-fluoro-, (aS)- (CAS 473552-27-1)
- 3-Propyl-benzenemethanol (CAS 125604-02-6)
- Benzenemethanol, 3-(2-propen-1-yl)- (CAS 106965-54-2)
- Benzenemethanol, 4-amino-3-(dimethylphosphinyl)- (CAS 2886000-74-2)
- Benzenemethanol, 3-chloro-4-hydroxy-5-nitro- (CAS 2883019-43-8)
- 4187-87-5 Benzenemethanol, alpha-ethynyl- (9CI) Benzyl alcohol, alpha-ethynyl- 1-Phenylprop-2-yn-1-ol AI3-24430 EINECS 224-064-6 alpha-Ethynylbenzenemethanol alpha-Ethynylbenzyl alcohol Ethynylphenylcarbinol NSC 4326 Phenylethynylcarbinol alpha-Phenylpropargyl alcohol 1-Phenylpropargyl alcohol 2-Propyn-1-ol, 1-phenyl- (CAS 4187-87-5)
- 41787-64-8 Benzenemethanol, 3,4-dimethoxy-alpha-((methylamino)methyl)-, (R)- (R)-3,4-Dimethoxy-alpha-((methylamino)methyl)benzenemethanol (-)-Normacromerine (CAS 41787-64-8)
Recommended Standards
- (4-Chloro-3-methoxyphenyl)methanol (CAS 13726-17-5)
- (2-Chloro-4-methoxypyridin-3-yl)methanamine (CAS 1378814-80-2)
- 2-Chloro-6-propoxypyrazine (CAS 136309-03-0)
- 3-Chloro-4-methoxy-1,2-benzenediamine (CAS 1378864-94-8)
- 1-(3-Chlorophenyl)-3-oxocyclohexanecarbonitrile (CAS 1956331-09-1)
- Irganox 1425 (CAS 65140-91-2)
- 1-(Pyridin-4-yl)ethanamine dihydrochloride (CAS 174132-32-2)
- N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-3,4-dimethoxybenzamide (CAS 636993-55-0)
- 2-chloro-2-cyclohexylacetonitrile (CAS 29770-68-1)
- 1-(2-Methoxyphenyl)cyclopropan-1-ol (CAS 1247446-34-9)
- Ethyl 1-((1H-indol-3-yl)methyl)piperidine-3-carboxylate (CAS 101602-77-1)
- Isothipendyl-d6 (CAS 1330265-10-5)
- 1-(4-Methylpyridin-3-yl)imidazolidin-2-one (CAS 1260008-61-4)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
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