5-Chloro-1H-indol-2-amine CAS 1378852-07-3
| CAS No. | 1378852-07-3 |
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-1H-indol-2-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-1H-indol-2-amine (CAS 1378852-07-3), molecular formula C8H7ClN2 and molecular weight 166.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 5-Chloro-1H-indol-2-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 166.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-1H-indol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-18-0)
- 6-Chloro-5-methyl-1H-indazole (CAS 1000341-02-5)
- 3-Chloro-7-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1000341-46-7)
- 5-Chloro-6-methyl-2H-indazole (CAS 1000343-64-5)
- 2-(2-Chloro-6-methylpyridin-3-yl)acetonitrile (CAS 1000514-91-9)
- 2-(6-Chloro-2-methylpyridin-3-yl)acetonitrile (CAS 1000529-85-0)
- 6-Chloro-2,4-dimethylpyridine-3-carbonitrile (CAS 101251-72-3)
- 2-Chloro-6-Methylimidazo[1,2-a]pyridine (CAS 1019019-96-5)
Recommended Standards
- 5-Chloro-3-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1378723-60-4)
- 5-Chloro-1-methyl-1H-indazole (CAS 1379091-92-5)
- 7-Chloro-3-methyl-1H-indazole (CAS 1378582-62-7)
- 6-(Chloromethyl)-4-methylpicolinonitrile (CAS 1393561-06-2)
- 5-(Aminomethyl)-n-ethylpyridine-2-sulfonamide (CAS 1463425-12-8)
- Methyl 4-oxo-6-phenyl-4H,5H-[1,2,3]triazolo[1,5-a]pyrazine-3-carboxylate (CAS 1443979-09-6)
- 5-Methyl-7-nitro-benzothiazole-2-carboxylic acid ethyl ester (CAS 40160-44-9)
- 2-{[4-ethyl-5-(1H-indol-3-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid (CAS 728031-59-2)
- 3-Cyclopropoxy-5-iodoisonicotinamide (CAS 1243353-99-2)
- (R)-N-Nitroso-N-2-propenyl-1-indanamine (CAS CATO-C3D-26187)
- 3-(4-(Aminomethyl)-1h-1,2,3-triazol-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 1247491-51-5)
- 2-[5-(2,4-Dichlorophenyl)-1H-pyrazol-1-yl]-4-(4-fluorophenyl)-1,3-thiazole (CAS 956206-48-7)
- 1-{5-[(propan-2-yloxy)methyl]-1,3,4-thiadiazol-2-yl}ethan-1-amine (CAS 1565395-60-9)
- Semaglutide Impurity 177 (CAS CATO-C4X-2226177)
Why CATO?
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