(3-Bromo-4-fluoro-2-methylphenyl)methanol CAS 1378875-50-3
| CAS No. | 1378875-50-3 |
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3-Bromo-4-fluoro-2-methylphenyl)methanol.
(3-Bromo-4-fluoro-2-methylphenyl)methanol (CAS 1378875-50-3) is a high-purity analytical reference standard with the molecular formula C8H8BrFO and a molecular weight of 219.05 g/mol.
(3-Bromo-4-fluoro-2-methylphenyl)methanol (C8H8BrFO) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3-Bromo-4-fluoro-2-methylphenyl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8BrFO |
| Molecular Weight | 219.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- (2-Bromo-5-fluorobenzyl)hydrazine (CAS 1016529-00-2)
- (5-Bromo-2-fluorobenzyl)hydrazine (CAS 1016699-41-4)
- (1s)-1-(4-Bromo-2-fluorophenyl)ethan-1-ol (CAS 1026088-11-8)
- 1-Bromo-4-ethoxy-2-fluorobenzene (CAS 107713-66-6)
- (R)-2-Bromo-1-(4-fluorophenyl)ethanol (CAS 1097211-38-5)
- 4-bromo-1-ethoxy-2-fluorobenzene (CAS 115467-08-8)
- (S)-2-Bromo-1-(3-fluorophenyl)ethan-1-ol (CAS 1176484-68-6)
- 5-Bromo-2-fluoro-3-methylbenzyl alcohol (CAS 1197944-22-1)
Recommended Standards
- (4-Fluoro-3-(bromomethyl)phenyl)methanol (CAS 1378867-70-9)
- 2-Bromo-4-fluoro-6-methylbenzyl alcohol (CAS 1379297-33-2)
- 2-Bromo-1-ethoxy-3-fluorobenzene (CAS 1375098-48-8)
- (2-Bromo-4-fluoro-5-methylphenyl)methanol (CAS 1379331-92-6)
- 3-Bromo-1-(phenylsulfonyl)-6-azaindole, 97% (CAS 1174038-64-2)
- Tert-butyl (R)-7-amino-5-thia-2-azaspiro[3.4]Octane-2-carboxylate 5,5-dioxide (CAS 2199282-23-8)
- 5-Fluoro-2-(pyrrolidin-3-yloxy)pyridine hydrochloride (CAS 1779126-62-3)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(5-methyl-1H-indol-3-yl)propanoic acid (CAS 114873-18-6)
- N-(Benzyloxycarbonyl)-L-β-chloroalanine Benzyl Ester (CAS 55822-82-7)
- 1H-Benzimidazole-7-carboxamide (CAS 188106-81-2)
- (2R,3S)-2-(1,3,5-trimethyl-1H-pyrazol-4-yl)tetrahydrofuran-3-amine dihydrochloride (CAS 1808654-34-3)
- N-(3,4-dimethoxyphenyl)-1-phenylcyclopentane-1-carboxamide (CAS 923844-17-1)
- Amino acid Impurity 4 (Z/E mixture) (CAS CATO-C1789414)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com