2-Ethynyl-4-fluoropyridine CAS 1379277-37-8
| CAS No. | 1379277-37-8 |
| Molecular Formula | C7H4FN |
| Molecular Weight | 121.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Ethynyl-4-fluoropyridine (CAS 1379277-37-8), a certified reference material (molecular formula C7H4FN, MW 121.11 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine substitution, an aromatic ring system, 2-Ethynyl-4-fluoropyridine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 121.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4FN |
| Molecular Weight | 121.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethynyl Standards
- 3-Ethynyl-2-fluoropyridine (CAS 933768-06-0)
- 5-Ethynyl-2-fluoropyridine (CAS 853909-08-7)
- 4-Ethynyl-1-methyl-1H-pyrazol-3-amine (CAS 2168087-35-0)
- 4-Ethynyl-3,5-dimethylisoxazole (CAS 668970-91-0)
- (6S)-6-Ethynyl-5-azaspiro[2.4]heptane (CAS 2410398-36-4)
- 1-Ethynyl-3-azabicyclo[4.1.0]Heptane (CAS 2387600-93-1)
- 5-Ethynyl-2-azabicyclo[4.1.0]Heptane (CAS 2387595-85-7)
- 6-Ethynyl-1-azaspiro[3.3]heptane (CAS 2287287-60-7)
Recommended Standards
- (S)-(-)-4-Amino-2-fluorobutyric acid (CAS 130695-33-9)
- N-Methylnitroacetamide-d3 (CAS 1795020-80-2)
- (S)-2-Amino-4-fluorobutanoic acid (CAS 121960-24-5)
- (R)-4-Amino-2-fluorobutanoic acid (CAS 65529-63-7)
- 2,4-Dichloro-6-methylpyrimidine-5-carbonitrile (CAS 56035-64-4)
- 4-((3-Chlorophenyl)thio)-2-(methylthio)-6-phenylpyrimidine-5-carbonitrile (CAS 341965-69-3)
- tert-Butyl (7-aminoheptyl)carbamate hydrochloride (CAS 62146-57-0)
- 1-(3-Chlorophenyl)ethane-1,2-diamine 2hcl (CAS 40658-82-0)
- 6-Chlorooxazolo[5,4-b]pyridine (CAS 886373-58-6)
- 1-(4-Methoxybenzyl)-1H-indole-2-carboxylic acid (CAS 179526-38-6)
- [3,4'-bipyridin]-5-ylmethanamine (CAS 1346686-57-4)
- 7-Methyl-2-(phenethylthio)-4H-pyrido[1,2-a][1,3,5]triazin-4-one (CAS 896325-78-3)
- N-(3,5-Dimethylphenyl)-2-(4-oxo-3,4-dihydrobenzo[b][1,4]thiazepin-5(2H)-yl)acetamide (CAS 862980-12-9)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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- 130,000+ catalog items in stock, COA supplied with every batch
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