2-Methyl-4-(trifluoromethyl)thiazole CAS 137929-13-6
| CAS No. | 137929-13-6 |
| Molecular Formula | C5H4F3NS |
| Molecular Weight | 167.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Methyl-4-(trifluoromethyl)thiazole (CAS 137929-13-6), a certified reference material (molecular formula C5H4F3NS, MW 167.15 g/mol) for analytical method development and quality control.
The molecular framework of 2-Methyl-4-(trifluoromethyl)thiazole (C5H4F3NS) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4F3NS |
| Molecular Weight | 167.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 2-(Trifluoromethyl)thiophen-3-amine (CAS 1822907-35-6)
- 4-(Trifluoromethyl)thiophen-2-amine (CAS 777846-37-4)
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- trans-4-(trifluoromethyl)cyclohexanamine (CAS 1073266-02-0)
- 4-Methyl-2-(trifluoromethyl)piperidine (CAS 1269151-53-2)
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Recommended Standards
- 4-Amino-2-(trifluoromethyl)thiophene (CAS 1378823-95-0)
- Methyl (2,2-difluoroethyl)alaninate (CAS 1513878-88-0)
- Ethyl 2,2-difluoro-3-(methylamino)propanoate (CAS 1346597-51-0)
- (R)-2-Amino-5,5-difluorohexanoic acid (CAS 154967-78-9)
- 1-(2,4-Dimethoxyphenyl)propan-2-one (CAS 831-29-8)
- 5-(tert-Butylthio)-N-cyclopropylpyridin-2-amine (CAS 1355179-46-2)
- (2R,3S,5R)-5-(4-amino-3-methyl-2,3-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 60192-55-4)
- 3-(1-Ethoxyethyl)-5-{4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenyl}-1,2,4-oxadiazole (CAS 1955520-12-3)
- Ethyl (1S,2S)-2-[[(S)-1-phenylethyl]amino]cyclopentanecarboxylate (CAS 359586-66-6)
- 3-Bromo-6-iodoimidazo[1,2-a]pyrazine (CAS 1464160-29-9)
- 3-((Phenyl(pyridin-4-yl)methyl)amino)propan-1-ol (CAS 585549-76-4)
- octyl propionate (CAS 142-60-9)
- 3-((4-(2-Chlorophenyl)piperazin-1-yl)sulfonyl)-1H-pyrazole-4-carbohydrazide (CAS 1370592-49-6)
- Allo-Thr7-Tirzepatide (CAS CATO-CPTD788933)
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