Ethyl 4-hydroxy-8-methoxy-5-methyl-2-naphthoate CAS 137932-77-5
| CAS No. | 137932-77-5 |
| Molecular Formula | C15H16O4 |
| Molecular Weight | 260.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 4-hydroxy-8-methoxy-5-methyl-2-naphthoate (C15H16O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Ethyl 4-hydroxy-8-methoxy-5-methyl-2-naphthoate (CAS 137932-77-5), molecular formula C15H16O4 and molecular weight 260.29 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H16O4 |
| Molecular Weight | 260.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
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Recommended Standards
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- (4-Aminocyclohexyl)methanol (CAS 89854-94-4)
- N-[(2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]glycine (CAS 1000932-56-8)
- 2-(((2-Fluoro-5-methylphenyl)amino)methyl)phenol (CAS 1037151-17-9)
- 2-(3,5-Dimethyl-1H-1,2,4-triazol-1-yl)acetic acid hydrochloride (CAS 1187927-35-0)
- 4-(Methoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylic Acid (CAS 18720-35-9)
- 3-Methyl-5-(1-pyrrolidin-3-yl-1h-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole (CAS 1708428-05-0)
- Semaglutide Impurity 12 (CAS CATO-C4X-222612)
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