8-Bromo-2-cyclopropylimidazo[1,2-a]pyridine CAS 1379347-80-4
| CAS No. | 1379347-80-4 |
| Molecular Formula | C10H9BrN2 |
| Molecular Weight | 237.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-Bromo-2-cyclopropylimidazo[1,2-a]pyridine (CAS 1379347-80-4), molecular formula C10H9BrN2 and molecular weight 237.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Bromo-2-cyclopropylimidazo[1,2-a]pyridine (C10H9BrN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 8-Bromo-2-cyclopropylimidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9BrN2 |
| Molecular Weight | 237.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-bromo-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine (CAS 1014614-11-9)
- 1-Bromo-3-cyclopropylimidazo[1,5-a]pyridine (CAS 1018603-14-9)
- 3-Bromo-2,4-dimethyl-1,8-naphthyridine (CAS 1019108-06-5)
- 8-Bromo-2-methylquinolin-5-amine (CAS 1023815-94-2)
- 4-Bromo-2-(o-tolyl)-1H-imidazole (CAS 1049117-87-4)
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- 4-Bromo-1-methyl-5-phenyl-1H-pyrazole (CAS 105994-77-2)
- 4-Bromo-5-methyl-2-phenyl-1H-imidazole (CAS 109892-69-5)
Recommended Standards
- 1-(3-(Bromomethyl)phenyl)-1H-pyrazole (CAS 1375148-70-1)
- (7-Bromoquinolin-6-yl)methanamine (CAS 1379365-17-9)
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- 1-(4-bromo-2-methylphenyl)-1H-pyrazole (CAS 1379371-45-5)
- 6-[2-(trifluoromethyl)phenoxy]pyridine-3-carbonitrile (CAS 1016747-55-9)
- 6-Methyl-2-(3-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160253-91-7)
- 4-((Methylsulfonyl)methyl)benzenesulfonyl chloride (CAS 1247407-55-1)
- Maltobionic Acid (CAS 534-42-9)
- Tinidazole Impurity 15 (CAS 1889-59-4)
- Netupitant Impurity 1 (CAS CATO-C4X-12231)
- 1,4-dimethyl 2-(difluoromethoxy)butanedioate (CAS 1803598-58-4)
- 1-{4-methoxypyrrolo[2,1-f][1,2,4]triazin-6-yl}propan-2-amine (CAS 1555667-17-8)
- Methyl (3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidine-3-carboxylate (CAS 1784747-39-2)
- Palmitoyl Tripeptide -5 · 2 TFA (CAS 623172-56-5)
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