3-(Bromomethyl)-5-fluorobenzoic acid CAS 1379351-68-4
| CAS No. | 1379351-68-4 |
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Bromomethyl)-5-fluorobenzoic acid.
3-(Bromomethyl)-5-fluorobenzoic acid (CAS 1379351-68-4), molecular formula C8H6BrFO2 and molecular weight 233.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Bromomethyl)-5-fluorobenzoic acid (C8H6BrFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Bromomethyl)-5-fluorobenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
Related Bromomethyl Standards
- 3-(Bromomethyl)-4-fluorobenzoic acid (CAS 89540-20-5)
- 4-(bromomethyl)-1-(trifluoromethyl)-1H-pyrazole (CAS 2169440-61-1)
- 4-(Bromomethyl)-3-fluorobenzoic Acid (CAS 361456-46-4)
- 5-(Bromomethyl)-2-fluorobenzoic acid (CAS 773100-76-8)
- Ethyl 5-(bromomethyl)furan-2-carboxylate (CAS 74675-71-1)
- Methyl 5-(bromomethyl)-1-methyl-1h-pyrazole-3-carboxylate (CAS 878744-22-0)
- methyl 5-(bromomethyl)-2-methyl-pyrazole-3-carboxylate (CAS 878744-19-5)
- 1-(Bromomethyl)-2-(2-fluoroethoxy)benzene (CAS 123644-43-9)
Recommended Standards
- 3-Bromo-2-fluorophenylacetic Acid (CAS 1375964-39-8)
- 3-Bromo-4-fluoro-5-methylbenzoic acid (CAS 1380310-06-4)
- 2-Bromo-4-fluoro-3-methylbenzoic acid (CAS 1373412-97-5)
- 2-bromo-3-fluoro-6-methylbenzoic acid (CAS 1427326-66-6)
- 5-Fluoro-1-(tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 68321-44-8)
- Isopropyl 6-amino-4-(2-chlorophenyl)-5-cyano-2-(((3-cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)methyl)-4H-pyran-3-carboxylate (CAS 445384-05-4)
- Methyl (2S,4S)-4-(1-naphthyloxy)-2-pyrrolidinecarboxylate (CAS 774576-73-7)
- tert-Butyl N-[1-(2-hydroxyphenyl)ethyl]carbamate (CAS 2126177-01-1)
- 1-(4-Bromophenyl)-3-((4-chlorophenyl)sulfonyl)propan-1-one (CAS 477334-52-4)
- 3-Aminobenzenecarboximidamide (CAS 3459-66-3)
- Imidazo[4,5-c]pyrazole (CAS 251-05-8)
- 5-Bromo-2-isobutylisoindolin-1-one (CAS 864866-84-2)
- 2,4-Diamino-6-Hydroxypyrimidine (CAS 195-66-4)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
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