2-Chloro-6-(trifluoromethyl)isonicotinamide CAS 1379355-32-4
| CAS No. | 1379355-32-4 |
| Molecular Formula | C7H4ClF3N2O |
| Molecular Weight | 224.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Chloro-6-(trifluoromethyl)isonicotinamide (CAS 1379355-32-4), molecular formula C7H4ClF3N2O and molecular weight 224.57 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-6-(trifluoromethyl)isonicotinamide (C7H4ClF3N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3N2O |
| Molecular Weight | 224.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-Chloro-4-(trifluoromethyl)nicotinamide (CAS 1201186-88-0)
- 2-Chloro-5-(trifluoromethyl)nicotinamide (CAS 1279217-36-5)
- 3-Chloro-6-(trifluoromethyl)picolinamide (CAS 1279815-47-2)
- 6-Chloro-5-(trifluoromethyl)nicotinamide (CAS 1360936-15-7)
- 2-Chloro-5-(trifluoromethyl)isonicotinamide (CAS 1416713-79-5)
- 5-Chloro-4-(trifluoromethyl)picolinamide (CAS 1805633-53-7)
- 5-Chloro-3-(trifluoromethyl)picolinamide (CAS 1805656-82-9)
- 2-Chloro-3-(trifluoromethyl)isonicotinamide (CAS 1807146-62-8)
Recommended Standards
- 4-Amino-5-(difluoromethyl)-6-fluoropicolinoyl chloride (CAS 1804510-38-0)
- 4-Amino-5-(difluoromethyl)-2-fluoronicotinoyl chloride (CAS 1804683-07-5)
- 4-Amino-3-(difluoromethyl)-5-fluoropicolinoyl chloride (CAS 1805078-82-3)
- Moxifloxacin Impurity N43 (CAS 1263376-71-1)
- 7-iodo-[1,2,4]triazolo[1,5-a]pyridine (CAS 690258-25-4)
- 5-fluoro-1H-pyrazol-3-amine (CAS 1159196-53-8)
- 6-Bromo-2H-benzo[e][1,2]thiazin-3(4H)-one 1,1-dioxide (CAS 1803567-42-1)
- Isavuconazole Impurity 181 (CAS CATO-C4X-1236181)
- Methyl 3-(2-methoxyphenyl)-2-methylbenzoate (CAS 1820606-98-1)
- 1-Butyl-2-[(E)-[(5-methylfuran-2-yl)methylidene]amino]-4,5-diphenyl-1H-pyrrole-3-carbonitrile (CAS 478032-88-1)
- 6-Bromo-7-methoxyisoquinolin-1(2H)-one (CAS 758710-73-5)
- 4-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridine (CAS 388118-59-0)
- Ethyl 2-(2-(trifluoromethyl)phenoxy)acetate (CAS 476155-15-4)
- Peptide 432 (CAS CATO-CPTD788432)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com