2-Iodo-4-(1-methylethyl)-6-(trifluoromethyl)pyrimidine CAS 1379357-39-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1379357-39-7
Molecular FormulaC8H8F3IN2
Molecular Weight316.06 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Iodo-4-(1-methylethyl)-6-(trifluoromethyl)pyrimidine CAS 1379357-39-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Iodo-4-(1-methylethyl)-6-(trifluoromethyl)pyrimidine.

2-Iodo-4-(1-methylethyl)-6-(trifluoromethyl)pyrimidine (CAS 1379357-39-7), molecular formula C8H8F3IN2 and molecular weight 316.06 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Iodo-4-(1-methylethyl)-6-(trifluoromethyl)pyrimidine (C8H8F3IN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Iodo-4-(1-methylethyl)-6-(trifluoromethyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H8F3IN2
Molecular Weight316.06 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1991
Halogen ContentF/I-containing
Nitrogen Atoms2

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