1-Fluoro-2,4-bis(bromomethyl)benzene CAS 1379366-74-1
| CAS No. | 1379366-74-1 |
| Molecular Formula | C8H7Br2F |
| Molecular Weight | 281.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Fluoro-2,4-bis(bromomethyl)benzene.
1-Fluoro-2,4-bis(bromomethyl)benzene (CAS 1379366-74-1) is a high-purity analytical reference standard with the molecular formula C8H7Br2F and a molecular weight of 281.95 g/mol.
Owing to fluorine/bromine substitution, an aromatic ring system, 1-Fluoro-2,4-bis(bromomethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Fluoro-2,4-bis(bromomethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7Br2F |
| Molecular Weight | 281.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Br-containing |
Related Fluoro Standards
- 1-Fluoro-3,5-bis(bromomethyl)benzene (CAS 19254-80-9)
- 5-FLuoro-4-iodo-2-nitroaniline (CAS 1219741-86-2)
- 4-Fluoro-2-iodo-6-nitroaniline (CAS 153505-44-3)
- 3-Fluoro-6-iodo-2-nitroaniline (CAS 1955534-80-1)
- 2-Fluoro-4-iodo-6-nitroaniline (CAS 517920-73-9)
- 2-Fluoro-6-iodo-4-nitroaniline (CAS 2091144-90-8)
- 2-Fluoro-6-iodomethoxymethoxybenzene (CAS 1160293-62-8)
- 2-Fluoro-1-iodo-3,4-dimethoxybenzene (CAS 1803783-41-6)
Recommended Standards
- 2-Bromo-4-(2-bromoethyl)-1-fluorobenzene (CAS 1341423-25-3)
- Nicotinic acid 4-formyl-phenyl ester (CAS 15131-72-3)
- 4-Bromo-1-(2-bromoethyl)-2-fluorobenzene (CAS 1331944-48-9)
- 1-Bromo-2-(2-bromoethyl)-4-fluorobenzene (CAS 1690789-24-2)
- (R)-2-([1,1'-Biphenyl]-4-ylmethyl)piperazine (CAS 1260608-89-6)
- 2,7-Naphthyridine (CAS 253-45-2)
- 4-(dimethylamino)-3,3-dimethylbutan-2-one (CAS 53921-82-7)
- 5-(1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one (CAS 1129294-89-8)
- 5,6-Dibromo-1H-benzo[d][1,2,3]triazole (CAS 716320-92-2)
- 1-(4-Chloro-2-fluorophenyl)-3-(3-fluorophenyl)propan-1-one (CAS 898767-55-0)
- 6-Bromo-2-(methylsulfonyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1046816-12-9)
- SDMA (p-hydroxyazobenzene-p′-sulfonate salt) (CAS 1266235-58-8)
- (E)-N-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-1,2,4-triazol-3-yl}-N'-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methanimidamide (CAS 860787-61-7)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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